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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ARHGAP1
All Species:
44.55
Human Site:
Y188
Identified Species:
89.09
UniProt:
Q07960
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q07960
NP_004299.1
439
50436
Y188
K
F
G
Q
K
I
F
Y
V
N
Y
L
S
E
L
Chimpanzee
Pan troglodytes
XP_508398
562
63325
Y311
K
F
G
Q
K
I
F
Y
V
N
Y
L
S
E
L
Rhesus Macaque
Macaca mulatta
XP_001101907
504
57584
Y253
K
F
G
Q
K
I
F
Y
V
N
Y
L
S
E
L
Dog
Lupus familis
XP_851463
698
78707
Y356
K
F
G
K
K
V
I
Y
F
N
S
L
S
E
L
Cat
Felis silvestris
Mouse
Mus musculus
Q5FWK3
439
50392
Y188
K
F
G
R
K
I
F
Y
V
N
Y
L
S
E
L
Rat
Rattus norvegicus
NP_001101217
439
50604
Y188
K
F
G
R
K
I
F
Y
V
N
Y
L
S
E
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_426422
437
50382
Y189
K
F
G
R
K
I
F
Y
V
N
F
L
S
E
L
Frog
Xenopus laevis
NP_001086509
435
50336
Y189
K
F
G
R
K
I
F
Y
A
N
Y
L
S
D
L
Zebra Danio
Brachydanio rerio
NP_001017781
434
49569
Y188
K
F
G
R
K
I
N
Y
I
N
Y
L
S
E
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTU3
476
54951
Y214
K
F
R
K
K
L
V
Y
I
S
S
L
D
E
L
Honey Bee
Apis mellifera
XP_624226
496
56427
Y250
K
F
G
R
K
M
M
Y
V
N
Y
L
E
E
L
Nematode Worm
Caenorhab. elegans
NP_001022390
444
50636
Y198
K
F
E
N
K
F
H
Y
V
M
C
I
D
E
L
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.7
86.1
30.5
N.A.
96.5
94.5
N.A.
N.A.
81
74.4
61.7
N.A.
33.1
43.5
37.8
N.A.
Protein Similarity:
100
77.9
86.3
42.8
N.A.
97.7
97
N.A.
N.A.
89.5
86.7
75.1
N.A.
53.1
61.6
57.6
N.A.
P-Site Identity:
100
100
100
66.6
N.A.
93.3
93.3
N.A.
N.A.
86.6
80
80
N.A.
46.6
73.3
46.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
100
100
N.A.
N.A.
100
93.3
93.3
N.A.
73.3
86.6
53.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
17
9
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
9
92
0
% E
% Phe:
0
100
0
0
0
9
59
0
9
0
9
0
0
0
0
% F
% Gly:
0
0
84
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
67
9
0
17
0
0
9
0
0
0
% I
% Lys:
100
0
0
17
100
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
9
0
0
0
0
0
92
0
0
100
% L
% Met:
0
0
0
0
0
9
9
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
9
0
0
9
0
0
84
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
9
50
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
9
17
0
75
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
9
9
0
67
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
100
0
0
67
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _